The latest Annual Report to the Nation on the Status of Cancer finds that, for all cancer sites combined, cancer death rates continued to decline in men, women, and children in the United States from 1999 to 2016. Overall cancer incidence rates, or rates of new cancers, decreased in men from 2008 to 2015, after increasing from 1999 to 2008, and were stable in women from 1999 to 2015. In a special section of the report, researchers looked at cancer rates and trends in adults ages 20 to 49. The annual report is a collaborative effort among the National Cancer…
Author: Brett Johnson
Soligenix is a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is currently an unmet medical need. Soligenix is a biotherapeutic business segment dedicated to the development of products for orphan diseases and areas where there are currently no drug therapies approved, such as Cutaneous T-Cell Lymphoma, oral mucositis, and pediatric Crohn’s disease. They are now conducting two Phase 3 clinical trials with multiple data reads through 2019 and early 2020. Their first Phase 3 trial, for cutaneous T-cell Lymphoma (or CTCL), used a novel photodynamic therapy for the first-line treatment of this…
New findings from a study by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, show that U.S. incidence rates for aggressive subtypes of uterine cancer rose rapidly among women ages 30 to 79 from 2000 to 2015. The findings also reveal racial disparities, including higher incidence of these aggressive subtypes and poorer survival—irrespective of subtype and cancer stage—among non-Hispanic black women than among women in other racial/ethnic groups. The study, published May 22, 2019 in the Journal of Clinical Oncology, used population data from NCI’s Surveillance, Epidemiology, and End Results (SEER) database to evaluate trends…
The Cancer Progress Report delivers crisp headlines of progress at emerging companies developing, in many cases, breakthroughs. It is a fast and efficient must read for anyone serious in the field. For companies it provides an economical means to accomplish the critical function of reaching and keeping the important informed as to progress. Editorial Content has three themes: Introductions to New Members Introduction to the company and what makes it unique. This 40 words linked to the Altru Cancer website and the company site for a full profile. Ongoing Coverage Member Progress. Update on newsworthy developments. Headline and first sentence…
A new diagnostic technology can predict how patients will respond different drugs or drug combinations before the patients take the drugs. Travera is using a breakthrough technology to measure which cancer drugs work against each individual’s unique cancer. This revolutionary diagnostic test will enable oncologists to quickly determine which drugs to prescribe based on the actual responses of their patients’ tumor cells. See Travera’s Profile.
“For me, this is one of the great honors of my research career,” says Dr. Ronald DePinho, who in 2009 won the prestigious Szent-Györgyi Prize for Progress in Cancer Research—and who has a touching personal tie to the namesake of the accolade. “I had the privilege of meeting Dr. Szent-Györgyi in my younger years, and was quite honored to later receive an award that bears his name.” It is natural to assume that to win the Szent-Györgyi Prize, one of oncology’s top laurels, a researcher must unravel a Gordian knot of genetic codes or discover some heretofore unknown cellular process.…
Immuno-oncology focusing on women’s cancers Technology Although cancer therapies have been developed that stimulate the immune system, these approaches have often proven ineffective because the cancers remain invisible to the immune system. Cancers cannot induce an immune response because they no longer express sufficient levels of key proteins on their cell surface. Antigen presentation is impaired thus presenting a weakened signal to which the cellular immune system can respond. The company’ peptide antigens can stimulate both T-killer cells and T-helper cells. When combined with its Polystart expression vector provides a competitive edge in the in vivo T-cell vaccine sector. Clinical…
Technology CEL-SCI Corporation is a late-stage biopharmaceutical company developing products for life-threatening diseases (such as cancer and infectious diseases). Its lead pipeline product – Multikine investigational immunotherapy (Leukocyte Interleukin, Injection) is a complex biological product containing a patented mixture of pro-inflammatory cytokines, lyphokines and chemokines. The aim of the Multikine immunotherapy treatment regimen is to break tumor-tolerance and up-end the tumor’s defense mechanisms by increasing tumor–specific infiltrating T-cells, NK cells and Neutrophils in the tumor and its microenvironment. The Multikine regimen is administered prior to any other therapy (immediately after diagnosis) when the immune system is thought to be most amenable…